03-06-2012 02:18 PM
a USB 6Gbps card should work in an S10 without issue. i've deployed various USB pci-e cards in thinkcentre and thinkstation systems but not specifically the S10.
i'd personally suggest something with an NEC (now renesas) chipset. one with a floppy power socket might be helpful if you need it to be powered and aren't currently using your floppy power lead.