Thanks for finally providing response from someone from Lenovo support.

I have already bios version BHCN32WW and Slow slew rate for ia domain value of fast/8 selected, and I still get audio desync when using Chrome, or Edge beta (with Chromium) browser. When using regular Microsoft Edge browser, I get no desync.

I have some serious DPC latency issues and audio crackling and popping as well, and I have literally tried everything to solve this.

Will Lenovo provide some software or BIOS updates to tackle those issues?

Thanks for the reponse from Lenovo Support. 

I already tried this, my laptop was in the repair center and before this I updated the BIOS as well. 

Again - just tried slew rate and both fast/8 and fast/16 leads to the same symptoms. I have perfect stream in "normal" Edge and desync in Chrome (all services affected, cable connected internet, external monitor, DSL 100 Mbit/s internet). The same issue with build in monitor (when the laptop is using the internal iGPU). I tried Realtek and Windows Audio drivers, spetial sound off, Windows Sonic, Dolby Atmos, different sound quality.

No problems on an older laptop with i3 3210m and 4GB Ram - all strems are ok in all browsers. 

Please provide some solution, will avoid to buy a new SSD for a new laptop for over 1000€. 

Guys, I think I found the solution to desync, audio cracking, popping and latency issues!!!!!!!

This evening I started to notice desync in Edge too. It was really going on to my nerves, so I have decided to try some more driver updates. I updated diferent drivers manualy in Device Manager (right click and then "Update driver"). However, that didn't solve the issue.

Then, I opened the "Storage controllers" section in Device Manager and there where two devices: "Standard NVM express controller" and "Microsoft storage spaces controller". I then right clicked on "Standard NVM express controller" and then "Update driver" , "Browse my computer for driver software" and "Let mi pick from list...". I then browsed into folder of the Intel IRST driver (c:\Drivers\Intel IRST Driver\Source\), and selected the first file. That was the Intel IRST driver downloaded from Lenovo support page for our laptop. After selecting that file there was "Intel Chipset SATA/PCIe RST Premium Controller" to select and install instead of "Standard NVM express controller". There will be message that it might not be compatible or something similiar, but just go with it. I then restarted laptop, and everything was working! No latency in LatencyMon, no delay in Chrome or Edge, even Latency Checker shows no more red bars!

I tested it only for 30 minutes, but I'm sure it solved all the issues. Maybe some other driver updates did the trick, but I think the one explained above did the trick. Just in case, I'm gonna post all my drivers in HTML again. Also, fast startup is off, but I don't think that matters too.

Please try and report back!

Link to HTML file with all my drivers: https://www120.zippyshare.com/v/drit3Ovr/file.html

IT WORKED?? 

still testing the above solution but so far 10 minutes without desync when i normally notice it at 5... i really think you cracked the code my dude thank you so f*n much!

Edit: Just watched a full episode of bbt on netflix without desync, tears of joy leave my body while i sit on my knees praying for the gods, this day will go down in history!