Yes, it works fine. I have a Yoga 2 Pro Model 20266, i7, 8 GB RAM, 256 SSD.
I bought a Samsung SSD EVO mSATA 1 TB at Newegg for $342.92.
I also bought the new Intel Wi-Fi/Bluetooth board, for about $40 at Amazon. 7260NGW Intel® Dual Band Wireless-AC 7260 802.11ac, Dual Band, 2x2 Wi-Fi + Bluetooth 4.0
I also needed a small Torx screwdriver set for the 11, T-5 screws on the bottom of the ultrabook. About $8 at Amazon.
Lastly, I bought a Sabrent USB 3.0 mSATA II-III/6G SSD Enclosure Adapter UASPEC-UKMS. This was $12.99 at Newegg but shipped from Adorama Camera. Extruded black anodized aluminum and included a cable. A very nice/functional piece of hardware. It is a beautiful thing.
I temporarly put the new 1TB SSD into the USB enclosure. No formatting needed.
I Upgraded the BIOS to version 76CN43WW.
Then I downloaded the Samsung Drive Cloning Software and cloned the 256 SSD (stock drive) to the 1TB SSD in the USB enclosure. This took several hours.
I removed the 11, T-5 screws and pulled the bottom of the ultrabook off near the hinges. It is held in place by strong magnets. Pretty cool design... no broken plastic tabs!
Removed the 1 tiny phillips screw holding the mSATA drive in place.
Swaped the drives. Swapped the W-Fi/Bluetooth card. Re-assembled and booted. Works like new money!
The only difficult part was the ultra small antenna connectors on the radio card. The ham-fisted need not apply for that job.
Lastly, download and run the Samsung Magician software. Do the OS Optimization. I set the over provisioning to the derfault of 10% or 93.15 GB. Create a Windows System Restore Point.
Option: I set the Samsung Rapid Mode.
Samsung Magician Benchmarks before/after setting Rapid Mode:
Sequential Read 545/5128. Sequential Write 512/3983; Random Read 82624/65928; Random Write 60440/39821. Rapid mode uses a cache and makes the numbers look wacky, but I like it.
Additional observation about new radio card: Speedtest.net showed my 5G connection is much faster than the old 2.4G connection. I'd quote speed numbers but they are too variable to be useful. Just know that it is more than double on 5G.
That's it. Easy upgrade, a bit over $400 in total but my ultrabook will be useful for another few years and I have a bonus of now owning the most kick-ass, external, 256 GB SSD USB 3.0 drive!