The X220multimedia card reader in the x220 works on the PCI bus and can read SDXC cards. I have seen comments here that it reads the UHS-1 cards. Can it make full use of the read/write speeds of the latest cards,such as the SanDisk Extreme Pro? Also, does it matter whether NTSF or exFAT is used when the card is used as a backup device, not intended for use in a camera? What are the advantages/disadvantages of using SDHC/SDXC cards for backup?